Peptide Immunoaffinity Enrichment Coupled with Mass Spectrometry for Peptide and Protein Quantification
نویسندگان
چکیده
منابع مشابه
Quantification of Proteins Using Peptide Immunoaffinity Enrichment Coupled with Mass Spectrometry
There is a great need for quantitative assays in measuring proteins. Traditional sandwich immunoassays, largely considered the gold standard in quantitation, are associated with a high cost, long lead time, and are fraught with drawbacks (e.g. heterophilic antibodies, autoantibody interference, 'hook-effect').(1) An alternative technique is affinity enrichment of peptides coupled with quantitat...
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ژورنال
عنوان ژورنال: Clinics in Laboratory Medicine
سال: 2011
ISSN: 0272-2712
DOI: 10.1016/j.cll.2011.07.004